The Toxicology Investigators Consortium 2024 Annual Report.

Authors

Kim Aldy
Shao Li
Mari Costantini
Alyssa Falise
Rachel Culbreth
Paul M Wax
Jeffery Brent
Toxicology Investigators Consortium Study Group
Alexandra Amaducci DO, Lehigh Valley Health NetworkFollow
Gillian A. Beauchamp MD, Lehigh Valley Health NetworkFollow
Matthew D. Cook DO, Lehigh Valley Health NetworkFollow
John DelBianco MD, Lehigh Valley Health NetworkFollow
Aaron B Deutsch DO, Lehigh Valley Health NetworkFollow
Natalie E. Ebeling-Koning DO, Lehigh Valley Health NetworkFollow
Derek J. Fikse DO, Lehigh Valley Health NetworkFollow
Kira Galeano, Lehigh Valley Health NetworkFollow
Timlin Glaser MD, Lehigh Valley Health NetworkFollow
Chase Jones DO, Lehigh Valley Health NetworkFollow
Kenneth D. Katz MD, Lehigh Valley Health NetworkFollow
Andrew L. Koons, Lehigh Valley Health NetworkFollow
Carl Levy DO, Lehigh Valley Health NetworkFollow
Ryan Surmaitis DO, Lehigh Valley Health NetworkFollow
Tyler Willing DO, Lehigh Valley Health NetworkFollow

Publication/Presentation Date

1-7-2026

Abstract

Established in 2010, the American College of Medical Toxicology (ACMT) Toxicology Investigators Consortium (ToxIC) Core Registry has systematically captured data from in-hospital and clinic-based medical toxicology physician consultations across the United States (US) and internationally. The ToxIC Core Registry contains deidentified patient data, including patient demographics, reason for medical toxicology evaluation, exposure agents, clinical signs and symptoms, treatments and antidotes administered, and mortality outcomes. This fifteenth annual report provides data from 8,868 patients entered into the Core Registry in 2024, bringing the total number of cases to 111,276 between 2010 and 2024. These cases were submitted by 41 participating sites encompassing 67 distinct hospitals over 23 US states and 3 international countries. In 2024, ethanol was the most commonly reported exposure agent class (17.8%), followed by opioids (15.8%), non-opioid analgesics (10.5%), and sympathomimetic agents (7.6%). A total of 107 fatalities were reported, corresponding to a case fatality rate of 1.2%. Additional descriptive analyses in this annual report were conducted to describe trends for opioid and psychoactive exposures between 2010 and 2024.

ISSN

1937-6995

Published In/Presented At

Aldy, K., Li, S., Costantini, M., Falise, A., Culbreth, R., Wax, P. M., Brent, J., & Toxicology Investigators Consortium Study Group (2026). The Toxicology Investigators Consortium 2024 Annual Report. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 10.1007/s13181-025-01099-0. Advance online publication. https://doi.org/10.1007/s13181-025-01099-0

Disciplines

Medicine and Health Sciences

PubMedID

41501581

Department(s)

Department of Emergency Medicine, Department of Emergency Medicine Faculty, Department of Emergency Medicine Residents, Toxicology Division, Fellows and Residents

Document Type

Article