Risk Factors for Restenosis After Carotid Revascularization: A Meta-Analysis of Hazard Ratios.
Publication/Presentation Date
5-1-2019
Abstract
BACKGROUND: Carotid artery restenosis after carotid endarterectomy (CEA) or carotid artery stenting (CAS) will occur in 3%-30% of cases. Restenosis can lead to more frequent clinical and imaging monitoring and the potential for reoperation. We sought to define the demographic, clinical, and radiographic characteristics that influence the restenosis risk after carotid revascularization.
METHODS: The present study was performed in accordance with the PRISMA (preferred reporting items for systematic reviews and meta-analyses) guidelines. A random effects model meta-analysis of hazard ratios (HRs) was conducted.
RESULTS: Eighteen studies with 17,106 patients were included. Diabetes (HR, 1.68; 95% confidence interval [CI], 1.00-2.83; I
CONCLUSIONS: Diabetes, dyslipidemia, female gender, renal failure, hypertension, and smoking were associated with an increased risk of restenosis, and patch endarterectomy and symptomatic status at presentation were associated with a decreased risk of carotid restenosis. Both female gender and current smoking status were only associated with recurrent stenosis after CEA, and hypertension was only associated with restenosis after CAS.
Volume
125
First Page
414
Last Page
424
ISSN
1878-8769
Published In/Presented At
Texakalidis, P., Tzoumas, A., Giannopoulos, S., Jonnalagadda, A. K., Jabbour, P., Rangel-Castilla, L., Machinis, T., Rivet, D. J., & Reavey-Cantwell, J. (2019). Risk Factors for Restenosis After Carotid Revascularization: A Meta-Analysis of Hazard Ratios. World neurosurgery, 125, 414–424. https://doi.org/10.1016/j.wneu.2019.02.065
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
30822589
Department(s)
Administration and Leadership
Document Type
Article