Preoperative Use of Statins in Carotid Artery Stenting: A Systematic Review and Meta-analysis.
Publication/Presentation Date
10-1-2018
Abstract
PURPOSE: To determine through meta-analysis whether administration of statins before carotid artery stenting (CAS) is associated with fewer periprocedural adverse events.
METHODS: All randomized and observational English-language studies of periprocedural statin administration prior to CAS that reported the outcomes of interest (stroke, transient ischemic attack, myocardial infarction, and death at 30 days) were included in a random-effects meta-analysis. The I
RESULTS: Eleven studies comprising 4088 patients were included. Patients who received statins prior to CAS had a significantly lower risk of stroke (OR 0.39, 95% CI 0.27 to 0.58, p< 0.01; I
CONCLUSION: Statin therapy prior to CAS is associated with decreased risk of perioperative stroke and death without any effect on the rates of transient ischemic attack or myocardial infarction.
Volume
25
Issue
5
First Page
624
Last Page
631
ISSN
1545-1550
Published In/Presented At
Texakalidis, P., Giannopoulos, S., Jonnalagadda, A. K., Chitale, R. V., Jabbour, P., Armstrong, E. J., Schwartz, G. G., & Kokkinidis, D. G. (2018). Preoperative Use of Statins in Carotid Artery Stenting: A Systematic Review and Meta-analysis. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 25(5), 624–631. https://doi.org/10.1177/1526602818794030
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
30101624
Document Type
Article