Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors: ASCO and SNO Endorsement of the Congress of Neurological Surgeons Guidelines.
Publication/Presentation Date
5-1-2019
Abstract
PURPOSE: The Congress of Neurological Surgeons (CNS) has developed a series of guidelines for the treatment of adults with metastatic brain tumors, including systemic therapy and supportive care topics. ASCO has a policy and set of procedures for endorsing clinical practice guidelines that have been developed by other professional organizations.
METHODS: Two CNS guidelines were reviewed for developmental rigor by methodologists, and an independent multidisciplinary Expert Panel was formed to review the content and assess agreement with the recommendations. The Expert Panel voted to endorse the two guidelines, and ASCO and Society for Neuro-Oncology (SNO) independently reviewed and approved the ASCO/SNO guideline endorsement.
RESULTS: The ASCO/SNO Expert Panel determined that the recommendations from the CNS anticonvulsants and steroids guidelines, published January 9, 2019, are clear, thorough, and based on the most relevant scientific evidence. ASCO/SNO endorsed these two CNS guidelines with minor alterations.
RECOMMENDATIONS: Key recommendations include the following: prophylactic antiepileptic drugs were not recommended for routine use; and corticosteroids, specifically dexamethasone, were recommended for temporary symptomatic relief in patients with neurologic symptoms and signs related to mass effect from brain metastases. Additional information is available at www.asco.org/neurooncology-guidelines .
Volume
37
Issue
13
First Page
1130
Last Page
1135
ISSN
1527-7755
Published In/Presented At
Chang, S. M., Messersmith, H., Ahluwalia, M., Andrews, D., Brastianos, P. K., Gaspar, L. E., Gatson, N. T. N., Jordan, J. T., Khasraw, M., Lassman, A. B., Maues, J., Mrugala, M., Raizer, J., Schiff, D., Stevens, G., Sumrall, A., van den Bent, M., & Vogelbaum, M. A. (2019). Anticonvulsant Prophylaxis and Steroid Use in Adults With Metastatic Brain Tumors: ASCO and SNO Endorsement of the Congress of Neurological Surgeons Guidelines. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 37(13), 1130–1135. https://doi.org/10.1200/JCO.18.02085
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
30883246
Department(s)
Administration and Leadership
Document Type
Article