What single-cell RNA sequencing taught us about
Publication/Presentation Date
1-1-2025
Abstract
BACKGROUND: The promoter methylation status of O-6-methylguanine-DNA methyltransferase (
METHODS: We used publicly available data from 3 recent single-cell/nucleus sequencing GBM studies that included
RESULTS: In the CPTAC study, a median of 0.82% and 5.7% of tumor cells expressed MGMT in the
CONCLUSION: Single-cell data suggest that
Volume
7
Issue
1
First Page
058
Last Page
058
ISSN
2632-2498
Published In/Presented At
Alnahhas, I., Khan, M. M., & Shi, W. (2025). What single-cell RNA sequencing taught us about MGMT expression in glioblastoma. Neuro-oncology advances, 7(1), vdaf058. https://doi.org/10.1093/noajnl/vdaf058
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
40351834
Department(s)
Administration and Leadership
Document Type
Article