Characterization of human endogenous retroviral envelope RNA transcripts.
Publication/Presentation Date
10-1-1985
Abstract
We characterized the structure of human endogenous retroviral env RNA transcripts by Northern blot hybridization and cDNA cloning. Polyadenylated 3.0- and 1.7-kilobase env RNAs can be identified in placenta, colon carcinoma, and breast carcinoma cells. We have obtained partial cDNA clones of both size classes of RNAs. Both env RNAs contained putative gp70 coding sequences; the 1.7-kilobase species, however, lacked sequences in the 3' env region which could specify a p15E analog. Both cDNA clones contained in-frame termination codons; thus, neither could encode full-length env proteins.
Volume
56
Issue
1
First Page
176
Last Page
182
ISSN
0022-538X
Published In/Presented At
Rabson, A. B., Hamagishi, Y., Steele, P. E., Tykocinski, M., & Martin, M. A. (1985). Characterization of human endogenous retroviral envelope RNA transcripts. Journal of virology, 56(1), 176–182. https://doi.org/10.1128/JVI.56.1.176-182.1985
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
3839854
Department(s)
Administration and Leadership
Document Type
Article