Effect of Gender, Age, and Profound Disease on Upper Airway Stimulation Outcomes.

Publication/Presentation Date

8-1-2020

Abstract

OBJECTIVE: To evaluate treatment outcomes of upper airway stimulation (UAS) in obstructive sleep apnea (OSA) patients based on patient age, gender, and preoperative disease severity.

METHODS: Retrospective chart review of patients undergoing UAS from 2014 to 2018 at a tertiary care center. Data collected included demographic information, implantation records, and pre- and postoperative polysomnography (PSG) results. Profound OSA was defined as AHI >65 and age ≥65 was considered advanced age. The primary outcome measured was initial treatment response, defined as a post-operative AHI < 20 with a >50% reduction from baseline.

RESULTS: 145 patients underwent UAS at our institution including 98 males and 47 females with a mean age of 61.7 ± 11.5 years, mean BMI of 29.1 ± 3.9 kg/m

CONCLUSION: Although the overall OSA population showed significant postoperative AHI reduction with UAS, patients age ≥65 years were less likely to have an initial response to treatment, when compared to their younger counterparts. A larger proportion of elderly patients and patients with profound OSA had residual moderate disease (AHI > 15) after UAS.

LEVEL OF EVIDENCE: 4.

Volume

129

Issue

8

First Page

772

Last Page

780

ISSN

1943-572X

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

32172600

Department(s)

Administration and Leadership

Document Type

Article

Link to Full Text

Share

COinS