Delayed radiation injury to the retrobulbar optic nerves and chiasm. Clinical syndrome and treatment with hyperbaric oxygen and corticosteroids.
Publication/Presentation Date
3-1-1990
Abstract
Thirteen patients with delayed radiation injury to the optic nerves and chiasm were treated with hyperbaric oxygen (HBO) and corticosteroids. These patients experienced painless, abrupt loss of vision in one (6 patients) or both (7 patients) eyes between 4 and 35 months after receiving radiation doses of at least 4500 cGy to the region of the chiasm. Diagnostic evaluation including neuro-imaging and lumbar puncture showed no recurrent tumor and no other cause for visual loss. No patient's vision improved during treatment or follow-up lasting between 1 and 4 years. There were no serious complications of treatment.
Volume
97
Issue
3
First Page
346
Last Page
351
ISSN
0161-6420
Published In/Presented At
Roden, D., Bosley, T. M., Fowble, B., Clark, J., Savino, P. J., Sergott, R. C., & Schatz, N. J. (1990). Delayed radiation injury to the retrobulbar optic nerves and chiasm. Clinical syndrome and treatment with hyperbaric oxygen and corticosteroids. Ophthalmology, 97(3), 346–351. https://doi.org/10.1016/s0161-6420(90)32582-4
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
2336273
Department(s)
Administration and Leadership
Document Type
Article