The antiphospholipid antibody syndrome: diagnostic aspects.
Publication/Presentation Date
12-1-2004
Abstract
PURPOSE OF REVIEW: The antiphospholipid antibody syndrome is an important cause of arterial and/or venous thrombosis. In this review the authors discuss recent trends in the clinical and laboratory diagnosis of this syndrome that are of relevance to ophthalmologists.
RECENT FINDINGS: The diagnostic criteria of antiphospholipid antibody syndrome have been reviewed and revalidated recently. Few prospective studies have been conducted to determine the prevalence of antiphospholipid antibodies in patients with retinal vascular occlusion and the spectrum of ophthalmologic findings in patients with established antiphospholipid syndrome. New antibody tests for antiphospholipid antibody syndrome are available with increased sensitivity and specificity, but lack of standardization, and interassay and interlaboratory variation makes it difficult to determine their clinical value.
SUMMARY: Ophthalmologists should be familiar with the spectrum of clinical manifestation of antiphospholipid syndrome, the diagnostic criteria of this disease, and be able to carry out a basic laboratory workup for this entity. A high index of suspicion for this disorder is also important in making the diagnosis.
Volume
15
Issue
6
First Page
483
Last Page
485
ISSN
1040-8738
Published In/Presented At
Behbehani, R., Sergott, R. C., & Savino, P. J. (2004). The antiphospholipid antibody syndrome: diagnostic aspects. Current opinion in ophthalmology, 15(6), 483–485. https://doi.org/10.1097/01.icu.0000144389.97491.52
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
15523192
Department(s)
Administration and Leadership
Document Type
Article