Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines.

Authors

• S A Karangwa
• P Dutkowski
• P Fontes
• P J Friend
• J V Guarrera
• J F Markmann
• H Mergental
• T Minor
• C Quintini
• M Selzner
• K Uygun
• C J Watson
• R J Porte

Publication/Presentation Date

10-1-2016

Abstract

With increasing demand for donor organs for transplantation, machine perfusion (MP) promises to be a beneficial alternative preservation method for donor livers, particularly those considered to be of suboptimal quality, also known as extended criteria donor livers. Over the last decade, numerous studies researching MP of donor livers have been published and incredible advances have been made in both experimental and clinical research in this area. With numerous research groups working on MP, various techniques are being explored, often applying different nomenclature. The objective of this review is to catalog the differences observed in the nomenclature used in the current literature to denote various MP techniques and the manner in which methodology is reported. From this analysis, we propose a standardization of nomenclature on liver MP to maximize consistency and to enable reliable comparison and meta-analyses of studies. In addition, we propose a standardized set of guidelines for reporting the methodology of future studies on liver MP that will facilitate comparison as well as clinical implementation of liver MP procedures.

Volume

16

Issue

10

First Page

2932

Last Page

2942

ISSN

1600-6143

Published In/Presented At

Karangwa, S. A., Dutkowski, P., Fontes, P., Friend, P. J., Guarrera, J. V., Markmann, J. F., Mergental, H., Minor, T., Quintini, C., Selzner, M., Uygun, K., Watson, C. J., & Porte, R. J. (2016). Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 16(10), 2932–2942. https://doi.org/10.1111/ajt.13843

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

27129409

Department(s)

Administration and Leadership

Document Type

Article