Objective oculomotor, vestibular, reaction time, and cognitive signatures of vestibular migraine.

Publication/Presentation Date

1-1-2026

Abstract

OBJECTIVE: To evaluate oculomotor, vestibular, reaction time, and cognitive (OVRT-C) function in patients with vestibular migraine (VM) using objective eye-tracking-based metrics and to identify patterns of dysfunction relative to healthy controls.

BACKGROUND: Vestibular migraine is a common yet underdiagnosed cause of vertigo. Diagnosis remains primarily clinical, because objective neurologic and vestibular findings are often absent or inconsistent. Quantitative methods capable of capturing the multisystem manifestations of VM may improve objective characterization of the disorder.

METHODS: Participants with a clinical diagnosis of vestibular migraine were recruited from a tertiary headache center and assessed using a battery of OVRT-C tests administered with a portable eye-tracking system (Spryson Dx-100;

RESULTS: A substantial proportion of VM patients aged 18 to 45 demonstrated abnormal OVRT-C performance compared with normative data, most prominently in horizontal and vertical saccades (54.3 and 51.4%,

CONCLUSION: Objective OVRT-C testing reveals quantifiable abnormalities in oculomotor, vestibular, and cognitive dysfunction in patients with vestibular migraine. These findings support the feasibility of eye-tracking-based multimodal assessments as complementary tools for characterizing vestibular migraine and warrant further validation in larger and longitudinal cohorts.

Volume

17

First Page

1789811

Last Page

1789811

ISSN

1664-2295

Disciplines

Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods

PubMedID

42246042

Department(s)

Administration and Leadership

Document Type

Article

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