Efficacy of fully covered self-expandable metal stents and comparison with conventional management for ERCP-related type II perforations: a systematic review and meta-analysis.
Publication/Presentation Date
11-1-2025
Abstract
BACKGROUND AND AIMS: Conservative management is often used in the management of ERCP-related type II perforations. In this meta-analysis, we have evaluated the efficacy of fully covered self-expandable metal stents (FCSEMSs) in the management of type II perforations and also compared these with conventional management.
METHODS: We reviewed several databases from inception to December 12, 2024. Outcomes of interest were clinical success, need for percutaneous catheter drainage (PCD) or surgery, pancreatitis, length of hospital stay, and mortality. Data were analyzed using a random effects model.
RESULTS: The rate of clinical success was significantly higher (OR, 9.96; 95% CI, 1.83-54.12), rate of surgery and need for PCD significantly lower (OR, 0.09; 95% CI, 0.01-0.63), and length of hospital stay significantly shorter (mean difference, -9.90; 95% CI, -17.61 to -2.20) in the FCSEMS group.
CONCLUSIONS: This meta-analysis demonstrates the superiority of FCSEMSs in achieving better outcomes compared with conventional management of type II perforations.
Volume
102
Issue
5
First Page
738
Last Page
742
ISSN
1097-6779
Published In/Presented At
Saeed, A., Yousuf, S., Zain, A., Imran, H., Tariq, M., Fazal, M. I., Shah, J., Radlinski, M., Gamboa, A., Xiao, Y., Kumar, A., Schlachterman, A., Kowalski, T., Adler, D. G., & Kamal, F. (2025). Efficacy of fully covered self-expandable metal stents and comparison with conventional management for ERCP-related type II perforations: a systematic review and meta-analysis. Gastrointestinal endoscopy, 102(5), 738–742.e2. https://doi.org/10.1016/j.gie.2025.05.022
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
40446855
Department(s)
Administration and Leadership
Document Type
Article