Superficial siderosis of the central nervous system: an underdiagnosed cause of sensorineural hearing loss and ataxia.
Publication/Presentation Date
5-1-1994
Abstract
Superficial siderosis of the central nervous system (CNS) is a rare but ultimately fatal disorder characterized by progressive hearing loss, ataxia, and dementia. Symptoms are caused by the deposition of hemosiderin in the CNS as a result of recurrent or persistent extravasation of blood into the cerebrospinal fluid. Sites most commonly involved include the cerebellum, brain stem, and eighth cranial nerve. In the past, diagnosis was most often made at autopsy, and this may account for the lack of reported cases in the otolaryngologic literature and the presumed rarity of the disorder. Now, diagnosis is confirmed by characteristic magnetic resonance imaging findings and treatment is targeted toward the source of bleeding. The diagnosis of superficial CNS siderosis should be entertained in all patients presenting with sensorineural hearing loss and ataxia.
Volume
15
Issue
3
First Page
415
Last Page
418
ISSN
0192-9763
Published In/Presented At
Pribitkin, E. A., Rondinella, L., Rosenberg, S.i, & Yousem, D. M. (1994). Superficial siderosis of the central nervous system: an underdiagnosed cause of sensorineural hearing loss and ataxia. The American journal of otology, 15(3), 415–418.
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
8579152
Department(s)
Administration and Leadership
Document Type
Article