Bone graft alternatives for spinal fusion.
Publication/Presentation Date
1-1-2003
Abstract
Bone grafting to achieve fusion is frequently performed in spinal surgery. Autograft is the gold standard bone graft material. However, due to limitations of supply and morbidity associated with the harvest of autograft, alternatives are being considered. Osteoconductive matrices, such as allograft, calcium or ceramic preparations are one such class of potential bone graft alternatives, but generally they lack osteoinductive properties. Recent attention has focused on osteoinductive materials such as demineralised bone matrix, recombinant bone morphogenetic proteins and bone marrow aspirates or blood product concentrates. These products may be combined with osteoconductive carriers and are clearly finding a place in the clinical arena.
Volume
17
Issue
6
First Page
391
Last Page
394
ISSN
1173-8804
Published In/Presented At
Grauer, J. N., Beiner, J. M., Kwon, B. K., & Vaccaro, A. R. (2003). Bone graft alternatives for spinal fusion. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 17(6), 391–394. https://doi.org/10.2165/00063030-200317060-00002
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
14614762
Department(s)
Administration and Leadership
Document Type
Article