Does Smoking Status Influence Health-Related Quality of Life Outcome Measures in Patients Undergoing ACDF?
Publication/Presentation Date
1-1-2021
Abstract
STUDY DESIGN: Retrospective comparative study.
OBJECTIVE: Whereas smoking has been shown to affect the fusion rates for patients undergoing an anterior cervical discectomy and fusion (ACDF), the relationship between smoking and health-related quality of life outcome measurements after an ACDF is less clear. The purpose of this study was to evaluate whether smoking negatively affects patient outcomes after an ACDF for cervical degenerative pathology.
METHODS: Patients with tumor, trauma, infection, and previous cervical spine surgery and those with less than a year of follow-up were excluded. Smoking status was assessed by self-reported smoking history. Patient outcomes, including Neck Disability Index, Short Form 12 Mental Component Score, Short Form 12 Physical Component Score (PCS-12), Visual Analogue Scale (VAS) arm pain, VAS neck pain, and pseudarthrosis rates were evaluated. Outcomes were compared between smoking groups using multiple linear and logistic regression, controlling for age, sex, and body mass index (BMI), among other factors. A
RESULTS: A total of 264 patients were included, with a mean follow-up of 19.8 months, age of 53.1 years, and BMI of 29.6 kg/m2. There were 43 current, 69 former, and 152 nonsmokers in the cohort. At baseline, nonsmokers had higher PCS-12 scores than current smokers (
CONCLUSIONS: Whereas nonsmokers had higher function and lower pain than former or current smokers preoperatively, smoking status overall was not found to be an independent predictor of outcome scores after ACDF. This supports the notion that smoking status alone should not deter patients from undergoing ACDF for cervical degenerative pathology.
Volume
11
Issue
1
First Page
50
Last Page
56
ISSN
2192-5682
Published In/Presented At
Mangan, J. J., Goyal, D. K. C., Divi, S. N., Bowles, D. R., Nicholson, K. J., Mujica, V. E., Lee, T. J., DePaola, R. V., Saline, A., Fang, T., Galetta, M. S., Kaye, I. D., Kurd, M. F., Woods, B. I., Radcliff, K. E., Rihn, J. A., Anderson, D. G., Hilibrand, A. S., Kepler, C. K., Vaccaro, A. R., … Schroeder, G. D. (2021). Does Smoking Status Influence Health-Related Quality of Life Outcome Measures in Patients Undergoing ACDF?. Global spine journal, 11(1), 50–56. https://doi.org/10.1177/2192568219890292
Disciplines
Business Administration, Management, and Operations | Health and Medical Administration | Management Sciences and Quantitative Methods
PubMedID
32875848
Department(s)
Administration and Leadership
Document Type
Article