T2-fluid attenuated inversion recovery mismatch in tumefactive multiple sclerosis.
Publication/Presentation Date
2-1-2023
Abstract
The T2-fluid attenuated inversion recovery (FLAIR) mismatch sign has been suggested as an imaging marker of isocitrate dehydrogenase-mutant 1p/19q non-codeleted gliomas with 100% specificity. Tumefactive demyelination is a common mimic of neoplasm that has led to unnecessary biopsies and even resections. We report a case of tumefactive multiple sclerosis in a 46-year-old male without prior symptomatic demyelinating episodes that demonstrates the T2-FLAIR mismatch sign. Our findings suggest the T2-FLAIR mismatch sign should not be used as a differential feature between glioma and tumefactive demyelination. Because typical isocitrate dehydrogenase-mutant 1p/19q non-codeleted gliomas typically do not demonstrate significant enhancement, such diagnosis should be reserved when post-contrast images are unavailable.
Volume
9
Issue
1
First Page
20220138
Last Page
20220138
ISSN
2055-7159
Published In/Presented At
Le, D., Trinh, K., Das, N., & Kuo, A. H. (2023). T2-fluid attenuated inversion recovery mismatch in tumefactive multiple sclerosis. BJR case reports, 9(1), 20220138. https://doi.org/10.1259/bjrcr.20220138
Disciplines
Medicine and Health Sciences
PubMedID
36873238
Department(s)
Fellows and Residents
Document Type
Article
