A Rare Case of Cutaneous Metastasis of Renal Cell Carcinoma to the Lateral Thigh.

Publication/Presentation Date

4-1-2023

Abstract

Renal cell carcinoma (RCC) is a common cancer type in the United States, and at the time of diagnosis, many patients already have metastatic disease. RCC typically metastasizes to the lungs, liver, and bones, with few cases manifesting cutaneous metastasis. Most incidences of RCC metastases reported in the literature have been on the face and scalp. We discuss a case of a 64-year-old male patient who presented with a history of RCC and a purpuric nodule on his lateral thigh. Histopathological examination revealed vacuolated cytoplasm with areas of cytoplasmic clearing; the cells stained positively for cytokeratin AE1/AE3, CAM5.2, and PAX8. Cutaneous metastatic RCC was subsequently diagnosed. Cutaneous manifestations of RCC, particularly to the thigh, remain a rare presentation of metastatic RCC.

Volume

15

Issue

4

First Page

37457

Last Page

37457

ISSN

2168-8184

Disciplines

Medicine and Health Sciences

PubMedID

37187636

Department(s)

Fellows and Residents

Document Type

Article

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