Ablation Length, Not Modality Type, Determines Healing Outcomes in Venous Leg Ulcers.

Publication/Presentation Date

8-29-2025

Abstract

OBJECTIVES: Early endovenous intervention of the saphenous system improves healing and recurrence of venous leg ulcers (CEAP-6). As ablative methods continue to evolve, it is essential to identify outcome differences between the various techniques. This study aims to compare wound healing rates between primary non-thermal [cyanoacrylate glue (CAG) or commercial polidocanol microfoam ablation (MFA)] and thermal with adjunct MFA.

METHODS: In this multi-center retrospective cohort study, patients with healed venous ulcers after non-thermal endovenous treatment were identified from four tertiary referral US institutions. Demographics, co-morbidities, procedural, and wound data were collected. Patients whose full-length great saphenous vein (GSV) was treated with a single non-thermal modality (CAG or MFA) were compared to those treated with RFA + MFA of the below knee segment. Multivariate linear regression was performed to identify predictors of wound healing.

RESULTS: 55 patients were identified (27 primary CAG or MFA and 28 RFA+MFA). The average age was 70±12, 56% were male, and 53% had BMI>30kg/m

CONCLUSIONS: Treatment of the full-length GSV with single non-thermal modality (CAG or MFA) or thermal plus MFA below the knee have comparable time to wound healing. This suggests comprehensive treatment, irrespective of modality, of the entire GSV to the ankle is the preferred approach for optimal wound healing in CEAP-6 patients.

First Page

102308

Last Page

102308

ISSN

2213-3348

Disciplines

Medicine and Health Sciences

PubMedID

40887034

Department(s)

Fellows and Residents

Document Type

Article

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