Acute lung injury: how to stabilize a broken lung.
Publication/Presentation Date
5-24-2018
Abstract
The pathophysiology of acute respiratory distress syndrome (ARDS) results in heterogeneous lung collapse, edema-flooded airways and unstable alveoli. These pathologic alterations in alveolar mechanics (i.e. dynamic change in alveolar size and shape with each breath) predispose the lung to secondary ventilator-induced lung injury (VILI). It is our viewpoint that the acutely injured lung can be recruited and stabilized with a mechanical breath until it heals, much like casting a broken bone until it mends. If the lung can be "casted" with a mechanical breath, VILI could be prevented and ARDS incidence significantly reduced.
Volume
22
Issue
1
First Page
136
Last Page
136
ISSN
1466-609X
Published In/Presented At
Nieman, G. F., Andrews, P., Satalin, J., Wilcox, K., Kollisch-Singule, M., Madden, M., Aiash, H., Blair, S. J., Gatto, L. A., & Habashi, N. M. (2018). Acute lung injury: how to stabilize a broken lung. Critical care (London, England), 22(1), 136. https://doi.org/10.1186/s13054-018-2051-8
Disciplines
Medicine and Health Sciences
PubMedID
29793554
Department(s)
Fellows and Residents
Document Type
Article