CRP Monitoring in Early Hospitalization: Implications for Predicting Outcomes in Patients with COVID-19.

Authors

Byron Avihai
Erin P Sundel
Eileen Lee
Patricia J Greenberg
Brennan P Cook
Nicole J Altomare
Tomohiro M Ko
Angelo I Chaia
Payal D Parikh
Martin J Blaser

Publication/Presentation Date

11-4-2023

Abstract

Elevated C-reactive protein (CRP) levels have been associated with poorer COVID-19 outcomes. While baseline CRP levels are higher in women, obese individuals, and older adults, the relationship between CRP, sex, body mass index (BMI), age, and COVID-19 outcomes remains unknown. To investigate, we performed a retrospective analysis on 824 adult patients with COVID-19 admitted during the first pandemic wave, of whom 183 (22.2%) died. The maximum CRP value over the first five hospitalization days better predicted hospitalization outcome than the CRP level at admission, as a maximum CRP > 10 mg/dL independently quadrupled the risk of death (

Volume

12

Issue

11

ISSN

2076-0817

Published In/Presented At

Avihai, B., Sundel, E. P., Lee, E., Greenberg, P. J., Cook, B. P., Altomare, N. J., Ko, T. M., Chaia, A. I., Parikh, P. D., & Blaser, M. J. (2023). CRP Monitoring in Early Hospitalization: Implications for Predicting Outcomes in Patients with COVID-19. Pathogens (Basel, Switzerland), 12(11), 1315. https://doi.org/10.3390/pathogens12111315

Disciplines

Medicine and Health Sciences

PubMedID

38003780

Department(s)

Fellows and Residents

Document Type

Article