ST-T wave abnormality in lead aVR and reclassification of cardiovascular risk (from the National Health and Nutrition Examination Survey-III).
Publication/Presentation Date
9-15-2013
Abstract
Electrocardiographic lead aVR is often ignored in clinical practice. The aim of this study was to investigate whether ST-T wave amplitude in lead aVR predicts cardiovascular (CV) mortality and if this variable adds value to a traditional risk prediction model. A total of 7,928 participants enrolled in the National Health and Nutrition Examination Survey (NHANES) III with electrocardiographic data available were included. Each participant had 13.5 ± 3.8 years of follow-up. The study sample was stratified according to ST-segment amplitude and T-wave amplitude in lead aVR. ST-segment elevation (>8 μV) in lead aVR was predictive of CV mortality in the multivariate analysis when not accounting for T-wave amplitude. The finding lost significance after including T-wave amplitude in the model. A positive T wave in lead aVR (>0 mV) was the strongest multivariate predictor of CV mortality (hazard ratio 3.37, p
Volume
112
Issue
6
First Page
805
Last Page
810
ISSN
1879-1913
Published In/Presented At
Badheka, A. O., Patel, N. J., Grover, P. M., Shah, N., Singh, V., Deshmukh, A., Mehta, K., Chothani, A., Hoosien, M., Rathod, A., Savani, G. T., Marzouka, G. R., Gupta, S., Mitrani, R. D., Moscucci, M., & Cohen, M. G. (2013). ST-T wave abnormality in lead aVR and reclassification of cardiovascular risk (from the National Health and Nutrition Examination Survey-III). The American journal of cardiology, 112(6), 805–810. https://doi.org/10.1016/j.amjcard.2013.04.058
Disciplines
Medicine and Health Sciences
PubMedID
23764245
Department(s)
Fellows and Residents
Document Type
Article