The use of sodium MRI in the diagnosis of an anaplastic astrocytoma during immunotherapy: a case report.
Publication/Presentation Date
3-1-2024
Abstract
Gliomas in the pediatric population are targeted with immune-modulating therapies. The gold standard imaging modality for diagnosis and monitoring treatment response is magnetic resonance imaging (MRI); however, the complex post-therapy-induced changes can make treatment response assessment difficult. These include radiation necrosis, pseudoresponse, and pseudoprogression, as well as more complex responses in the setting of immunotherapy. We report a case of an 11-year-old male with a supratentorial astrocytoma (WHO grade 3) that underwent treatment with immunotherapy. There was a clinical concern for progression due to increased fluid-attenuated inversion recovery (FLAIR) hyperintensity at the site of the primary neoplasm during immunotherapy. However, the Sodium (
Volume
40
Issue
3
First Page
965
Last Page
967
ISSN
1433-0350
Published In/Presented At
De Leon-Benedetti, L., Narayanan, S., Lee, V. K., Panigrahy, A., Boada, F., & Bhatia, A. (2024). The use of sodium MRI in the diagnosis of an anaplastic astrocytoma during immunotherapy: a case report. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 40(3), 965–967. https://doi.org/10.1007/s00381-023-06195-6
Disciplines
Medicine and Health Sciences
PubMedID
37878058
Department(s)
Fellows and Residents
Document Type
Article