Unveiling the Hidden Stroke Threat in Patients With Atrial Fibrillation and Primary Hyperparathyroidism.

Authors

• Georges Khattar
• Samer Asmar
• Elie Bou Sanayeh
• Praneeth Keesari
• Wissam Rahi
• Fouad Sakr
• Michel Khoury
• Michael Cinelli
• Samantha Lee
• Mitchell Weinberg
• Marcin Kowalski
• Valay Parikh

Publication/Presentation Date

5-1-2024

Abstract

Recent American College of Cardiology (ACC), American Heart Association (AHA), American College of Clinical Pharmacy (ACCP), and Heart Rhythm Society (HRS) guidelines suggest that patients with atrial fibrillation (AF) at intermediate to low annual risk of ischemic stroke can benefit from consideration of factors that might modify their risk of stroke. The role of nontraditional risk factors, such as primary hyperparathyroidism (PHPT), remains unexplored. In our study, we investigated the potential association between PHPT and the risk of ischemic stroke in patients with AF. Using data from the Nationwide Inpatient Sample Database, a retrospective cohort study focused on the adult population with AF, we stratified the participants based on PHPT presence. Demographic information, co-morbidities, and hospitalization details were extracted using International Classification of Diseases, Tenth revision codes. Propensity score matching was applied, encompassing over 20 confounding variables, including the risk factors outlined in the CHA

Volume

218

First Page

94

Last Page

101

ISSN

1879-1913

Published In/Presented At

Khattar, G., Asmar, S., Sanayeh, E. B., Keesari, P., Rahi, W., Sakr, F., Khoury, M., Cinelli, M., Lee, S., Weinberg, M., Kowalski, M., & Parikh, V. (2024). Unveiling the Hidden Stroke Threat in Patients With Atrial Fibrillation and Primary Hyperparathyroidism. The American journal of cardiology, 218, 94–101. https://doi.org/10.1016/j.amjcard.2024.03.003

Disciplines

Medicine and Health Sciences

PubMedID

38452840

Department(s)

Fellows and Residents

Document Type

Article