Nasofrontal meningiomas: retrospective series and review of literature.
Publication/Presentation Date
6-29-2023
Abstract
INTRODUCTION: Lesions affecting the anterior skull base and involving the paranasal sinuses (PNS), nasal cavity (NC), and orbit are infrequent and include predominantly a wide variety of sinonasal malignancies. Less than 3% of intracranial meningiomas extend extracranially and involve PNS and NC. Given their relatively low incidence, little is known about the treatment outcome of this subset of meningiomas.
METHODS: Systematic literature and retrospective review of own institutional series of midline anterior skull base meningiomas with significant PNS and NC involvement were performed.
RESULTS: Overall, 21 patients-16 in the literature review group and 5 of our institutional series-were included. Eleven (52.4%) patients had had a prior surgery for midline anterior skull base meningioma. Of patients having reported WHO grade, two were WHO II. Gross total resection was achieved in 16 (76.2%) of patients, utilizing solely transcranial approach in 15 patients, combined endoscopic and transcranial in five patients and purely endoscopic in one patient. Postoperative radiotherapy was administered in three (14.3%) patients, all after total resection via transcranial route, without a history of prior treatment. A postoperative cerebrospinal fluid leak was reported in four (10%) patients, requiring surgical repair in two. There were no reports of postoperative meningitis. No neurological complications were observed except of a reported worsening of vision in one patient.
CONCLUSION: Midline anterior skull base meningiomas infrequently extend significantly into the PNS and NC. Despite their significant involvement, along with concomitant involvement of orbit, gross total resection is possible in the majority of cases with low morbidity using either purely transcranial or combined endoscopic/transcranial approach.
Volume
46
Issue
1
First Page
158
Last Page
158
ISSN
1437-2320
Published In/Presented At
Peto, I., Monsour, M., Piper, K., Flores-Milan, G., Pressman, E., Tabor, M., & van Loveren, H. (2023). Nasofrontal meningiomas: retrospective series and review of literature. Neurosurgical review, 46(1), 158. https://doi.org/10.1007/s10143-023-02053-w
Disciplines
Medicine and Health Sciences
PubMedID
37386320
Department(s)
Fellows and Residents
Document Type
Article