QT interval prolongation and rhabdomyolysis associated with diphenhydramine toxicity: a case report.
Publication/Presentation Date
5-21-2020
Abstract
Diphenhydramine is a widely available, over-the-counter medication used for allergies and as a sleeping aid. When used in prescription doses, it is generally safe. Overdose of the medication has been associated with dangerous and life-threatening outcomes. Our case describes diphenhydramine toxicity manifesting with two rare but potentially life-threatening complications, rhabdomyolysis, and QT prolongation. Laboratory testing for diphenhydramine levels are not widely available. We recommend a high degree of suspicion for these complications when evaluating patients with diphenhydramine overdose, to adequately manage and prevent untoward outcomes.
Volume
10
Issue
2
First Page
151
Last Page
153
ISSN
2000-9666
Published In/Presented At
Ali, Z., Khan, M., Ullah, W., Kpehor, A. A., & Cheema, M. A. (2020). QT interval prolongation and rhabdomyolysis associated with diphenhydramine toxicity: a case report. Journal of community hospital internal medicine perspectives, 10(2), 151–153. https://doi.org/10.1080/20009666.2020.1749511
Disciplines
Medicine and Health Sciences
PubMedID
32850053
Department(s)
Fellows and Residents
Document Type
Article