Targeting glutathione with the triterpenoid CDDO-Im protects against benzo-a-pyrene-1,6-quinone-induced cytotoxicity in endothelial cells.
Publication/Presentation Date
11-1-2020
Abstract
Epidemiological studies have exhibited a strong correlation between exposure to air pollution and deaths due to vascular diseases such as atherosclerosis. Benzo-a-pyrene-1,6-quinone (BP-1,6-Q) is one of the components of air pollution
Volume
474
Issue
1-2
First Page
27
Last Page
39
ISSN
1573-4919
Published In/Presented At
Shukla, H., Lee, H. Y., Koucheki, A., Bibi, H. A., Gaje, G., Sun, X., Zhu, H., Li, Y. R., & Jia, Z. (2020). Targeting glutathione with the triterpenoid CDDO-Im protects against benzo-a-pyrene-1,6-quinone-induced cytotoxicity in endothelial cells. Molecular and cellular biochemistry, 474(1-2), 27–39. https://doi.org/10.1007/s11010-020-03831-6
Disciplines
Medicine and Health Sciences
PubMedID
32715408
Department(s)
Department of Emergency Medicine, Fellows and Residents
Document Type
Article
COinS