Evidence for a bicarbonate "escort" site in Haemophilus influenzae beta-carbonic anhydrase .
Publication/Presentation Date
5-4-2010
Abstract
The Haemophilus influenzae beta-carbonic anhydrase (HICA) allosteric site variants V47A and G41A were overexpressed and purified to homogeneity. These variants have k(cat)/K(m) values similar to that of the wild-type enzyme and exhibit a similar dramatic decrease in catalytic activity at pH
Volume
49
Issue
17
First Page
3640
Last Page
3647
ISSN
1520-4995
Published In/Presented At
Rowlett, R. S., Hoffmann, K. M., Failing, H., Mysliwiec, M. M., & Samardzic, D. (2010). Evidence for a bicarbonate "escort" site in Haemophilus influenzae beta-carbonic anhydrase . Biochemistry, 49(17), 3640–3647. https://doi.org/10.1021/bi100328j
Disciplines
Medicine and Health Sciences
PubMedID
20359198
Department(s)
Fellows and Residents
Document Type
Article
COinS