Atypical case of syphilitic hepatitis.
Publication/Presentation Date
3-17-2021
Abstract
A 31-year-old immunocompetent, heterosexual man with no relevant medical history presented with 1 week of jaundice, abdominal pain, cough and headache. Examination revealed scleral icterus, right upper quadrant tenderness and hepatomegaly. Initial investigations revealed hyperbilirubinaemia and elevated transaminases. Serum studies were positive for antinuclear antibodies, antimitochondrial antibodies, and herpes simplex virus IgM. Despite being started on intravenous acyclovir, his bilirubin and transaminase levels continued to rise. He was subsequently tested for syphilis given his maculopapular rash on the soles of his feet and it returned positive. He improved clinically with the initiation of penicillin. In this case, we will discuss the presentation, diagnosis and treatment of syphilitic hepatitis.
Volume
14
Issue
3
ISSN
1757-790X
Published In/Presented At
Goldberg, E., Edwards, B., & Krill, K. (2021). Atypical case of syphilitic hepatitis. BMJ case reports, 14(3), e237851. https://doi.org/10.1136/bcr-2020-237851
Disciplines
Medicine and Health Sciences
PubMedID
33731401
Department(s)
Fellows and Residents
Document Type
Article