Cholestyramine: use as a new therapeutic approach for chlordecone (kepone) poisoning.
Publication/Presentation Date
2-24-1978
Abstract
In rats, as reported in humans, chlordecone (Kepone) is excreted predominantly in the feces. Cholestyramine, an anion exchange resin, binds chlordecone in rat intestine, increases its excretion into the feces, and decreases its content in the tissues. The resin appears to offer a practical method for treating chronic poisoning with this and possibly with other lipophilic toxins.
Volume
199
Issue
4331
First Page
893
Last Page
895
ISSN
0036-8075
Published In/Presented At
Boylan, J. J., Egle, J. L., & Guzelian, P. S. (1978). Cholestyramine: use as a new therapeutic approach for chlordecone (kepone) poisoning. Science (New York, N.Y.), 199(4331), 893–895. https://doi.org/10.1126/science.74852
Disciplines
Medicine and Health Sciences
PubMedID
74852
Department(s)
Department of Medicine
Document Type
Article
COinS