An exaggerated augmentation of renal calcium excretion after oral glucose ingestion in patients with renal hypercalciuria.
Publication/Presentation Date
5-1-1978
Abstract
The calciuric response to an oral glucose load (100 g) was determined in 16 patients with calcium oxalate urolithiasis (seven with renal hypercalciuria and nine with absorptive hypercalciuria) and seven normal subjects. The rates of renal calcium excretion increased significantly after glucose ingestion in all three groups. The calciuric response in patients with absorptive hypercalciuria and intestinal hyperabsorption of calcium was indistinguishable from that of normal subjects. However, the calcium excretions were significantly higher during 1 hr preceding and 3 hr after glucose ingestion in patients with renal hypercalciuria (with presumed "renal leak" of calcium) than in normal subjects. The increment in the calcium excretion rate was also higher in patients with renal hyperacalciuria, particularly during the 2nd hour of glucose ingestion. The results provide a further support for the concept of different etiologies of renal and absorptive hypercalciurias.
Volume
15
Issue
6
First Page
486
Last Page
488
ISSN
0021-0005
Published In/Presented At
Barilla, D. E., Townsend, J., & Pak, C. Y. (1978). An exaggerated augmentation of renal calcium excretion after oral glucose ingestion in patients with renal hypercalciuria. Investigative urology, 15(6), 486–488.
Disciplines
Medicine and Health Sciences
PubMedID
348635
Department(s)
Department of Medicine
Document Type
Article