Lactic acidosis in theophylline overdose.
Publication/Presentation Date
7-1-1989
Abstract
An 18-year-old man with theophylline overdose developed an increased anion gap metabolic acidosis. Serum lactate levels were markedly elevated. A direct correlation was found between the increasing theophylline level, clinical hyperadrenergic state, and the worsening acidosis. Early hemoperfusion reversed the acidosis, the elevated serum theophylline level, and the hyperadrenergic state. This case substantiates the role of lactate accumulation in the metabolic acidosis associated with isolated theophylline toxicity.
Volume
7
Issue
4
First Page
417
Last Page
418
ISSN
0735-6757
Published In/Presented At
Leventhal, L. J., Kochar, G., Feldman, N. H., Podolsky, S. M., & Stanek, M. S. (1989). Lactic acidosis in theophylline overdose. The American journal of emergency medicine, 7(4), 417–418. https://doi.org/10.1016/0735-6757(89)90052-1
Disciplines
Medicine and Health Sciences
PubMedID
2567599
Department(s)
Department of Medicine
Document Type
Article