Patient Preferences for Novel Therapy: An N-of-1 Trial of Garlic in the Treatment for Hypertension.
Publication/Presentation Date
11-1-1993
Abstract
The authors used the N-of-1 clinical trial methodology to obtain insights about a patient's preference for garlic for the management of his hypertension. The 61-year-old man received garlic, 500 mg by mouth three times a day (3 weeks), or identical placebo (3 weeks) in three treatment pairs. While the patient was taking garlic the mean systolic blood pressure decreased by 2 mm Hg (95% confidence interval 0.4 to 4.7, p < 0.05), and the diastolic blood pressure decreased by 2.4 mm Hg (95% confidence interval 0.4 to 4, p < 0.025). The treatment effect of garlic was small, but the patient believed continuing garlic for the management of his hypertension was justified.
Volume
8
Issue
11
First Page
619
Last Page
621
ISSN
0884-8734
Published In/Presented At
Estrada, C. A., & Young, M. J. (1993). Patient preferences for novel therapy: an N-of-1 trial of garlic in the treatment for hypertension. Journal Of General Internal Medicine, 8(11), 619-621.
Disciplines
Medical Sciences | Medicine and Health Sciences
PubMedID
8289103
LVHN link
http://search.ebscohost.com/login.aspx?direct=true&db=mnh&AN=8289103&site=ehost-live&scope=site
Department(s)
Department of Medicine, Department of Medicine Faculty
Document Type
Article