Noise induced hearing loss in fetal sheep.
Publication/Presentation Date
4-1-1994
Abstract
The auditory brainstem response (ABR) was recorded in utero from chronically instrumented fetal sheep prior to and following exposure of pregnant ewes to intense broadband noise (120 dB SPL for 16 h). ABRs were elicited by clicks and tone bursts (0.5, 1, 2, and 4 kHz) delivered through a bone oscillator secured to the fetal skull. Latency-intensity functions for most of the four vertex-positive waves (labelled I-IV) were prolonged and ABR thresholds were temporarily elevated by an average of 8 dB following the noise exposure. Results show that exogenous sounds can penetrate the uterus and result in alterations of the fetal ABR.
Volume
74
Issue
1-2
First Page
221
Last Page
230
ISSN
0378-5955
Published In/Presented At
Griffiths, S. K., Pierson, L. L., Gerhardt, K. J., Abrams, R. M., & Peters, A. J. (1994). Noise induced hearing loss in fetal sheep. Hearing research, 74(1-2), 221–230. https://doi.org/10.1016/0378-5955(94)90190-2
Disciplines
Medicine and Health Sciences
PubMedID
8040092
Department(s)
Department of Obstetrics and Gynecology
Document Type
Article