Reproductive outcome in patients with diminished ovarian reserve.
Publication/Presentation Date
10-1-2001
Abstract
OBJECTIVE: To compare reproductive outcome between women with normal ovarian reserve and women with abnormal ovarian reserve.
DESIGN: Retrospective.
SETTING: Tertiary care center.
PATIENT(S): Nine thousand eight hundred and two patients who had basal follicle-stimulating hormone (FSH) concentrations measured as part of an infertility evaluation.
INTERVENTION(S): Monitoring of early pregnancy.
MAIN OUTCOME MEASURE(S): Pregnancy loss rates, live birth rates.
RESULT(S): Of 1,034 patients with diminished ovarian reserve (DOR) (FSH > or =14.2 IU/L), 28 (2.7%) conceived. Twenty of these pregnancies (20/28; 71.4%) were lost in the first trimester. Pregnancy loss rates in women with DOR were 57.1% in womenold, 63.5% in women 35-40 years old, and 90.0% in women >40 years old. These rates of pregnancy loss were significantly higher compared to age-matched patients with normal ovarian reserve.
CONCLUSIONS(S): Women with DOR have exceedingly high rates of pregnancy loss, regardless of age. Women with diminished ovarian reserve should be counseled that, in addition to a low probability of conception, live birth rates are poor.
Volume
76
Issue
4
First Page
666
Last Page
669
ISSN
0015-0282
Published In/Presented At
Levi, A. J., Raynault, M. F., Bergh, P. A., Drews, M. R., Miller, B. T., & Scott, R. T., Jr (2001). Reproductive outcome in patients with diminished ovarian reserve. Fertility and sterility, 76(4), 666–669. https://doi.org/10.1016/s0015-0282(01)02017-9
Disciplines
Medicine and Health Sciences
PubMedID
11591396
Department(s)
Department of Obstetrics and Gynecology
Document Type
Article