Establishing paternity using minisatellite DNA probes when the putative father is unavailable for testing.

Publication/Presentation Date

7-1-1988

Abstract

A paternity case involving a putative father who had died a few years earlier in an automobile accident was referred to the laboratory for testing. The child and his mother, the deceased's parents, and nine of the deceased's siblings were available for analysis. As previously reported, paternity testing using red blood cell groups, human leukocyte antigens (HLA), red blood cell enzymes, serum proteins, and immunoglobulin allotypes gave a cumulative paternity index of 43,300 and a combined probability of paternity equal to 99.998%. RFLP analysis using Hinf I and Sau 3A single digests and the minisatellite deoxyribonucleic acid (DNA) probes 15.1.11.4 and 6.3 showed no exclusion of paternity and gave nearly conclusive evidence that the putative father was the biological father of the child.

Volume

33

Issue

4

First Page

921

Last Page

928

ISSN

0022-1198

Disciplines

Medicine and Health Sciences

PubMedID

2902188

Department(s)

Department of Pathology and Laboratory Medicine

Document Type

Article

Share

COinS