Determination of zinc in whole blood, plasma and serum using Zeeman effect flame atomic absorption spectroscopy.

Publication/Presentation Date

10-15-1985

Abstract

Methods are presented for the determination of zinc in whole blood, plasma and serum using Zeeman effect flame atomic absorption spectroscopy and a flame microsampling funnel. Whole blood was diluted 1/25 with 0.10 mol/l hydrochloric acid; plasma and serum were diluted 1/5 with deionized water. Concentrations could be read directly from standards prepared in human blood pools. The within-run relative standard deviation (RSD) was 0.50%, 0.82% and 0.61% for whole blood specimens with concentrations of 4 360 micrograms/l, 5 967 micrograms/l and 8 297 micrograms/l, respectively. The within-run RSD was 2.09%, 1.16% and 0.62% for plasma specimens with zinc concentrations of 442 micrograms/l, 976 micrograms/l and 1 731 micrograms/l, respectively. The within-run RSD was 1.18%, 1.22% and 1.02% for serum specimens with zinc concentrations of 492 micrograms/l, 1 023 micrograms/l and 1 533 micrograms/l, respectively. The detection limit was 3.6 micrograms/l.

Volume

151

Issue

3

First Page

237

Last Page

243

ISSN

0009-8981

Disciplines

Medicine and Health Sciences

PubMedID

4053384

Department(s)

Department of Pathology and Laboratory Medicine

Document Type

Article

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