Breast tumor vascularity identified by contrast enhanced ultrasound and pathology: initial results.
Publication/Presentation Date
3-1-2000
Abstract
Quantifiable measures of vascularity obtained from contrast enhanced color flow images were correlated with pathologic vascularity measurements in ten female patients with a solid breast mass. Each patient received Levovist Injection (Berlex Laboratories Inc., Montville, NJ). Color flow images pre- and post-contrast were obtained using an HDI 3000 unit (ATL, Bothell, WA) before removing the mass for pathologic vascularity assessments. Image-processing techniques were used to obtain both the ultrasound and pathologic vascularity measurements. Multiple linear regression found significant correlations for ultrasonic vascularity measurements post contrast and pathology (P = 0.02 and 0.06). No correlations were found between pre-contrast ultrasound and pathology. In conclusion, post-contrast ultrasonic flow measures provide a non-invasive measure of breast tumor neovascularity. However, the patient population is small, and until further patients are analyzed, these conclusions are preliminary.
Volume
38
Issue
1-8
First Page
105
Last Page
109
ISSN
0041-624X
Published In/Presented At
Chaudhari, M. H., Forsberg, F., Voodarla, A., Saikali, F. N., Goonewardene, S., Needleman, L., Finkel, G. C., & Goldberg, B. B. (2000). Breast tumor vascularity identified by contrast enhanced ultrasound and pathology: initial results. Ultrasonics, 38(1-8), 105–109. https://doi.org/10.1016/s0041-624x(99)00146-8
Disciplines
Medicine and Health Sciences
PubMedID
10829638
Department(s)
Department of Pathology and Laboratory Medicine
Document Type
Article