Influence of Age and Type 1 Diabetes Mellitus on Serological Test for Celiac Disease in Children.
Purpose: Serological tests of tissue transglutaminase (TTG) and deamidated gliadin (DGP) antibodies for celiac disease diagnosis show conflicting correlation with histology in young children and in type 1 diabetes mellitus (T1DM). Tests' ability to predict histology and cutoff values based on age and T1DM was evaluated.
Methods: A retrospective study of children who had celiac serological tests between 6/1/2002 and 12/31/2014 at a pediatric hospital.
Results: TTG IgA displayed similar results in predicting histology between
Conclusion: TTG IgA is sufficient for the
Published In/Presented At
Maheshwari, A., He, Z., Weidner, M. N., Lin, P., Bober, R., & Del Rosario, F. J. (2021). Influence of Age and Type 1 Diabetes Mellitus on Serological Test for Celiac Disease in Children. Pediatric gastroenterology, hepatology & nutrition, 24(2), 218–229. https://doi.org/10.5223/pghn.2021.24.2.218
Medicine and Health Sciences | Pediatrics
Department of Pediatrics