Sleep Disturbances in Schizophrenia.
Publication/Presentation Date
12-1-2015
Abstract
Sleep disturbances are prevalent in patients with schizophrenia and play a critical role in the morbidity and mortality associated with the illness. Subjective and objective assessments of sleep in patients with schizophrenia have identified certain consistent findings. Findings related to the sleep structure abnormalities have shown correlations with important clinical aspects of the illness. Disruption of specific neurotransmitter systems and dysregulation of clock genes may play a role in the pathophysiology of schizophrenia-related sleep disturbances. Antipsychotic medications play an important role in the treatment of sleep disturbances in these patients and have an impact on their sleep structure.
Volume
38
Issue
4
First Page
777
Last Page
792
ISSN
1558-3147
Published In/Presented At
Kamath J, Virdi S, Winokur A. Sleep Disturbances in Schizophrenia. Psychiatr Clin North Am. 2015 Dec;38(4):777-92. doi: 10.1016/j.psc.2015.07.007. Epub 2015 Aug 22. PMID: 26600108.
Disciplines
Medicine and Health Sciences | Psychiatry
PubMedID
26600108
Department(s)
Department of Psychiatry
Document Type
Article