TRH response pattern in adolescent schizophrenic males.
Publication/Presentation Date
12-1-1984
Abstract
A marked elevation in human growth hormone (GH) following intravenous infusion of thyrotropin releasing hormone (TRH) was seen in three of seven adolescent male schizophrenic patients receiving neuroleptic drugs, and in one of five controls matched for age, sex, and developmental stage, receiving the same drugs. A positive family history for schizophrenia was noted in all three schizophrenic 'responders' but in only one of the remaining patients. The response patterns of thyroid stimulating hormone (TSH), triiodothyronine (T3), and thyroxine (T4) following TRH infusion were not significantly different in the two groups. No significant correlations were found between T3, T4, TSH, or GH response patterns and age of patient, duration of illness, medication dose or duration, weight change, or hours of sleep preceding testing.
Volume
145
First Page
649
Last Page
651
ISSN
0007-1250
Published In/Presented At
DeMilio L. (1984). TRH response pattern in adolescent schizophrenic males. The British journal of psychiatry : the journal of mental science, 145, 649–651. https://doi.org/10.1192/bjp.145.6.649
Disciplines
Psychiatry
PubMedID
6439274
Department(s)
Department of Psychiatry
Document Type
Article