Extracellular Vesicles' Role in Angiogenesis and Altering Angiogenic Signaling.

Publication/Presentation Date

1-3-2024

Abstract

Angiogenesis, the process of new blood vessels formation from existing vasculature, plays a vital role in development, wound healing, and various pathophysiological conditions. In recent years, extracellular vesicles (EVs) have emerged as crucial mediators in intercellular communication and have gained significant attention for their role in modulating angiogenic processes. This review explores the multifaceted role of EVs in angiogenesis and their capacity to modulate angiogenic signaling pathways. Through comprehensive analysis of a vast body of literature, this review highlights the potential of utilizing EVs as therapeutic tools to modulate angiogenesis for both physiological and pathological purposes. A good understanding of these concepts holds promise for the development of novel therapeutic interventions targeting angiogenesis-related disorders.

Volume

12

Issue

1

ISSN

2076-3271

Disciplines

Medicine and Health Sciences

PubMedID

38249080

Department(s)

Department of Surgery, Department of Surgery Residents, Fellows and Residents

Document Type

Article

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