The Nb rat: prostatic adenocarcinoma model.

Publication/Presentation Date

3-1-1979

Abstract

The Noble rat prostatic adenocarcinoma is an animal model which is used to study human prostatic carcinoma. It mimics the human condition in histology, in biochemistry with the production of acid phosphatase, and in tumor growth which is relatively constant. Additionally, it is hormonally dependent and metastasizes. This animal model should provide an avenue for the evaluation of cytotoxic chemotherapeutic agents heretofore receiving little attention from the urologic community.

Volume

16

Issue

5

First Page

353

Last Page

359

ISSN

0021-0005

Disciplines

Medicine and Health Sciences

PubMedID

429131

Department(s)

Department of Surgery

Document Type

Article

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