Therapeutic manipulation of Nb rat prostatic adenocarcinomas: chemotherapeutic evaluation of autonomous tumors.
Publication/Presentation Date
11-1-1979
Abstract
Nb rat autonomous prostatic adenocarcinomas were transplanted into several groups of synergeneic Nb rats. Chemotherapy using 5-fluorouracil, methotrexate, Adriamycin, and cyclophosphamide was evaluated. Significance was seen with the use of these agents with varying doses. Cyclophosphamide and 5-fluorouracil treated animals had complete tumor regression whereas Adriamycin and methotrexate treated animals had cessation of tumor volume increase in some groups after chemotherapy; however, neither agent causes complete tumor regression.
Volume
17
Issue
3
First Page
203
Last Page
206
ISSN
0021-0005
Published In/Presented At
Drago, J. R., Goldman, L. B., Maurer, R. E., Gershwin, M. E., & Eckels, D. D. (1979). Therapeutic manipulation of Nb rat prostatic adenocarcinomas: chemotherapeutic evaluation of autonomous tumors. Investigative urology, 17(3), 203–206.
Disciplines
Medicine and Health Sciences
PubMedID
500317
Department(s)
Department of Surgery
Document Type
Article