The Noble rat bladder cancer model. FANFT-induced tumors.

Authors

J R Drago

Publication/Presentation Date

3-1-1984

Abstract

This laboratory unit has been working with the Nb rat prostate adenocarcinoma model for the last several years and has recently used this model system to study efficacy of various chemotherapeutic agents in FANFT-induced bladder carcinomas in this rat strain. The purpose of this project is to identify factors and chemotherapeutic agents that might be useful for treatment of human bladder carcinoma. It is proposed that the use of the Nb rat be utilized to develop a data base to advance understanding of the management of bladder carcinoma induced by FANFT ingestion in Nb rats. Conventional cytotoxic agents and new combination chemotherapy will be utilized intravesically and systemically.

Volume

53

Issue

5

First Page

1093

Last Page

1099

ISSN

0008-543X

Disciplines

Medicine and Health Sciences

PubMedID

6692301

Department(s)

Department of Surgery

Document Type

Article

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