The induction of NB rat prostatic carcinomas.
Publication/Presentation Date
1-1-1984
Abstract
The NB rat prostate adenocarcinoma model is one in which microscopic carcinoma can be induced via the use of testosterone and estrogen silastic implants. There is an incidence of large, grossly-positive tumors; which approaches 10% to 15%. Seventy-three percent of the animals subjected to this induction method for periods of 9 to 18 months developed at least microscopic carcinoma. The earliest appearance microscopic foci of carcinoma was after three months of implantation, in which one of 30 animals so treated did show carcinoma. However, 88% of the animals treated for 18 months or longer showed microscopic carcinoma.
Volume
4
Issue
4-5
First Page
255
Last Page
256
ISSN
0250-7005
Published In/Presented At
Drago J. R. (1984). The induction of NB rat prostatic carcinomas. Anticancer research, 4(4-5), 255–256.
Disciplines
Medicine and Health Sciences
PubMedID
6486730
Department(s)
Department of Surgery
Document Type
Article