"The induction of NB rat prostatic carcinomas." by J R Drago
 

The induction of NB rat prostatic carcinomas.

Authors

J R Drago

Publication/Presentation Date

1-1-1984

Abstract

The NB rat prostate adenocarcinoma model is one in which microscopic carcinoma can be induced via the use of testosterone and estrogen silastic implants. There is an incidence of large, grossly-positive tumors; which approaches 10% to 15%. Seventy-three percent of the animals subjected to this induction method for periods of 9 to 18 months developed at least microscopic carcinoma. The earliest appearance microscopic foci of carcinoma was after three months of implantation, in which one of 30 animals so treated did show carcinoma. However, 88% of the animals treated for 18 months or longer showed microscopic carcinoma.

Volume

4

Issue

4-5

First Page

255

Last Page

256

ISSN

0250-7005

Disciplines

Medicine and Health Sciences

PubMedID

6486730

Department(s)

Department of Surgery

Document Type

Article

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