Noble PRST-1 Ca prostate adenocarcinoma study on noble rats: preliminary study on new androgen sensitive tumor.

Publication/Presentation Date

1-1-1989

Abstract

The Nb rat prostatic adenocarcinoma model has served as an animal model for testing various chemotherapeutic agents. Herein this preliminary report, the tumor Nb PRST-1 Ca was evaluated in 25 animals with testosterone, dihydrotestosterone, orchiectomized and control treatments. Tumor growth curves were determined and show a significant difference on day 13 (T-test) between the control group and treatment groups. Metastases were found in the lungs of all animals and a remarkable rounding of the liver was noted in the androgen treatment groups.

Volume

3

Issue

5

First Page

335

Last Page

337

ISSN

0258-851X

Disciplines

Medicine and Health Sciences

PubMedID

2519875

Department(s)

Department of Surgery

Document Type

Article

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