The hemodynamic effects of intravenous ranitidine in intensive care unit patients: a double-blind prospective study.
Publication/Presentation Date
12-1-1988
Abstract
The hemodynamic effects of intravenous ranitidine were studied in a prospective double-blind fashion in postoperative intensive care unit patients to determine if this H2 blocker produced the same transient fall in mean arterial pressure and systemic vascular resistance known to occur with cimetidine infusion. We found no statistically significant hemodynamic changes from baseline associated with infusion of 50 mg ranitidine over a 5-minute period. The different chemical ring structure of ranitidine and its effect on H2 vascular and cardiac receptors may account for these observations.
Volume
28
Issue
12
First Page
1098
Last Page
1100
ISSN
0091-2700
Published In/Presented At
Onofrey, D., Kelly, K. M., Gentili, D. R., Benjamin, E., & Iberti, T. J. (1988). The hemodynamic effects of intravenous ranitidine in intensive care unit patients: a double-blind prospective study. Journal of clinical pharmacology, 28(12), 1098–1100. https://doi.org/10.1002/j.1552-4604.1988.tb05722.x
Disciplines
Medicine and Health Sciences
PubMedID
3243926
Department(s)
Department of Surgery
Document Type
Article