Exercise-based cardiac rehabilitation after transcatheter aortic valve replacement: a systematic review and meta-analysis of randomized controlled trials.
Publication/Presentation Date
2-2-2026
Abstract
BACKGROUND: Many patients remain functionally limited after transcatheter aortic valve replacement (TAVR) despite successful correction of aortic stenosis. Exercise-based cardiac rehabilitation (EBCR) is effective in other cardiac populations, but its benefits after TAVR remain uncertain. This study evaluated the impact of EBCR on functional capacity, cardiac function, quality of life, and safety outcomes in post-TAVR patients.
METHODS: A systematic review and meta-analysis of randomized controlled trials (RCTs) published through February 2025 was conducted using major databases. Outcomes were pooled using mean differences or risk ratios with 95% confidence intervals.
RESULTS: Six RCTs with 272 patients were included. No significant difference was found between EBCR and usual care for peak VO
CONCLUSION: EBCR did not significantly improve outcomes after TAVR; however, near-significant trends in functional capacity warrant further large-scale investigation.
PROTOCOL REGISTRATION: PROSPERO ID CRD420250652719.
First Page
1
Last Page
12
ISSN
1744-8298
Published In/Presented At
Khan, U., Abdelgalil, M. S., Khan, M. H., Ali, J., Majeed, Z., Amin, A. M., Nawaz, A., Younas, H. M. W., Abuelazm, M., & Aamir, M. (2026). Exercise-based cardiac rehabilitation after transcatheter aortic valve replacement: a systematic review and meta-analysis of randomized controlled trials. Future cardiology, 1–12. Advance online publication. https://doi.org/10.1080/14796678.2026.2615390
Disciplines
Medicine and Health Sciences
PubMedID
41630560
Department(s)
Fellows and Residents
Document Type
Article