Head Up Cardiopulmonary Resuscitation: Novel Physiological Discoveries and Latest Clinical Outcomes.

Publication/Presentation Date

8-1-2025

Abstract

Despite decades of research, survival rates following cardiac arrest remain dismal. The recent use of pressure-volume (PV) loop analysis has provided important insights into the underlying physiology of cardiopulmonary resuscitation (CPR). During conventional CPR (C-CPR), ventricular ejection is limited, contributing to poor circulatory effectiveness. In contrast, automated head-up CPR (AHUP-CPR)-which combines active compression-decompression (ACD) CPR, an impedance threshold device (ITD), and controlled head-thorax elevation-generates favorable negative intrathoracic pressure, promoting cerebral venous drainage and increases right heart preload, resulting in enhanced stroke volume, cardiac output, and end-tidal CO

Volume

13

Issue

8

ISSN

2375-1916

Disciplines

Medicine and Health Sciences

PubMedID

41648073

Department(s)

Fellows and Residents, Department of Emergency Medicine Residents

Document Type

Article

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