Laser Doppler velocimetry study of retinal circulation in diabetes mellitus.
Publication/Presentation Date
7-1-1986
Abstract
Bidirectional laser Doppler velocimetry and monochromatic fundus photography were used to investigate retinal circulation in 26 normal subjects and in 51 insulin-treated diabetic patients with no retinopathy, background retinopathy (BDR), proliferative retinopathy (PDR), and patients with PDR who had been treated by panretinal photocoagulation (PDR-PRP). Measurements were obtained from main temporal retinal vessels in each eye. Venous diameter at the site of laser Doppler velocimetry measurements was significantly greater than normal in patients with BDR and PDR. The maximum velocity of red blood cells was significantly lower than normal in eyes with diabetic retinopathy. Calculated volumetric blood flow rate, however, was not significantly different from normal in eyes with no retinopathy, BDR, and PDR, and was significantly decreased from normal in patients with PDR who had been treated by panretinal photocoagulation. A comparison between this technique and the fluorescein dye dilution technique is provided.
Volume
104
Issue
7
First Page
991
Last Page
996
ISSN
0003-9950
Published In/Presented At
Grunwald, J. E., Riva, C. E., Sinclair, S. H., Brucker, A. J., & Petrig, B. L. (1986). Laser Doppler velocimetry study of retinal circulation in diabetes mellitus. Archives of ophthalmology (Chicago, Ill. : 1960), 104(7), 991–996. https://doi.org/10.1001/archopht.1986.01050190049038
Disciplines
Medicine and Health Sciences
PubMedID
2942132
Department(s)
Department of Medicine
Document Type
Article